Airdrie United turned on the style to leave Berwick Rangers rooted to the bottom of the Second Division table.
A well-placed cross from Ricky Waddle picked out Allan Russell, who headed the Diamonds into a 17th minute lead.
Visiting keeper Gary O'Connor made some excellent saves before Stuart Noble fired home on the turn and Stephen McKeown netted from the penalty spot.
Only one goal was added in the second half when sub Brian Prunty played in McKeown, who buried his shot.
Airdrie Utd: Robertson, McKenna, Lovering (Prunty 49), McDonald, Smyth, Sharp (Donnelly 46), Smith, McKeown, Russell (Gillies 76), Noble, Waddle. Subs Not Used: Jenkins, Hollis.
Goals: Russell 17, Noble 34, McKeown 42 pen, 61.
Berwick Rangers: O'Connor, Lennox, Noble, Horn (Bolochoweckyj 25), Smith, Fraser (Greenhill 29), McLeish, Swanson, Diack, Gemmill, Little (McMullan 85). Subs Not Used: Mark Stevenson, Flockhart.
Booked: Swanson, Bolochoweckyj, Gemmill.
Ref: A Law