Deveronvale are aiming to be the first Highland League side to progress to the Scottish Cup quarter finals since 1977.
Deveronvale lost out to Partick Thistle in 2001
The part-timers from Banff host First Division Partick Thistle, the 1921 winners of the tournament, on Saturday.
"We've been in the cup before but as a club we've never come as far as this," said manager Gregg Carrol.
"We're realistic obviously because Partick are a good side, and nine out of 10 times they'll beat us, but this might be our time."
Deveronvale have already knocked out Fraserburgh, Montrose and Elgin City and will be boosted by a sell-out crowd at their Princess Royal Stadium.
"We should be at full strength on Saturday, apart from Paul Urquhart who works as a plumber," says Deveronvale boss Gregg Carrol," added Carrol.
"A cast-iron water pipe went through his hand at work this week and he obviously misses out. He's been in a lot of pain."
The club have been given the green light to play striker Ian Murray, but only after he negotiated emergency leave from the North Sea oil rig where he works and was helicopted to dry land.
Division Three Elgin City, who were the last Highland League side to reach the quarters, were Deveronvale's third-round victims.
Vale led 4-0 in the first half but were eventually clinging on at 5-4.
"We've had Partick watched twice and we've been impressed," said Carrol.
"They're full-time and we know their fitness levels will tell at the end of the game.
"It would be great if we could start like we did against Elgin but certainly not have to hold on in the way we did.
"It'll be a full house of 2,700. We want to give a good account of the club and, if we lose, certainly not make fools of ourselves."
The teams have met in the Scottish Cup before, with Deveronvale suffering a second round 3-0 loss at Firhill in January 2001.