Shaun Maloney scored twice as Aston Villa ran riot at the Racecourse to reach the Carling Cup third round.
The Scot curled home the opener from the left side of box on 29 minutes.
Chris Llewellyn was denied a Wrexham equaliser by a fine save from Stuart Taylor, but Luke Moore's floated header doubled Villa's lead moments later.
Nigel Reo-Coker slotted in Villa's third on 62 minutes, Maloney grabbed his second 10 minutes later and Marlon Harewood hit the fifth from a corner.
Wrexham: Michael Jones, Spender, Pejic, Steve Evans, Valentine,
Murtagh (Marc Williams 55), Mackin, Mark Jones,
Eifion Williams (Taylor 79), Proctor (Johnson 61), Llewellyn.
Subs Not Used: Anthony Williams, Mike Williams.
Aston Villa: Taylor, Gardner, Mellberg, Cahill, Barry,
Agbonlahor, Osbourne, Reo-Coker (Petrov 67), Maloney, Moore,
Subs Not Used: Carson, Laursen, Young, Carew.
Goals: Maloney 30, Moore 52, Reo-Coker 62, Maloney 72,
Ref: Graham Laws (Tyne & Wear).