Liverpool boss Rafael Benitez is keen to gain revenge for Arsenal's 3-0 Premiership win over his side when facing the Gunners in the Carling Cup.
Benitez and Wenger will both field weakened sides at Anfield
Ahead of Tuesday's quarter-final, he said: "Arsenal are a good team - we have not forgotten losing 3-0 to them at the Emirates and want to win this.
"Arsenal have lots of good youngsters they paid big money for so whatever team they put out it will be difficult.
"The Carling Cup may be fourth in lists of importance but we want to win it."
Rotating the team is the only choice I have, the only way we can survive
Arsenal boss Arsene Wenger
Benitez has revealed that he is set to play a weakened side at Anfield to give some of his more important players a much-needed rest.
A busy festive period ends with the two teams meeting once again in a potentially-explosive FA Cup third round tie on 6 January.
"It is clear we will need to change some players but I do not know how many," added Benitez.
"We need to use different players because you cannot play with the same ones in every competition, especially at Christmas.
"Arsenal can change as well and use some young players. When you pay millions for Theo Walcott at 17, you must use him."
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Gunners boss Arsene Wenger said rotating his squad is the only way to get through the busy Christmas and new year period.
"Our heavy schedule at the moment is a consequence of doing well in the Carling Cup, doing well in the Champions League and because we had to pre-qualify for the Champions League," said Wenger.
"That gave us two extra games and pushed the Wigan game into an already busy time of the year.
"I have rotated the team lately - and I will continue to do that because I have absolutely no choice. It is the only way to survive."
Arsenal keeper Manuel Almunia is set to captain the side at Anfield and he says his side must be wary of a Liverpool backlash.
"It will certainly be more difficult at Anfield," confirmed the Spaniard.
"Liverpool have just had a big defeat to us, so I am sure they will be looking for revenge.
"It is the same as the Everton game in the last round, though, because everyone thought we were too young to win there.
"We will give 100% and make it very difficult."