Nottingham Forest made it to the Carling Cup second round on the night when their top-flight record of 42 games unbeaten was eclipsed by Arsenal.
Gareth Taylor awoke Forest from their slumber by bundling home the opener 10minutes before the break.
The striker converted Paul Evans' free-kick for his third goal of the season.
Scunthorpe's resistance finally wilted 12 minutes from time, when Marlon King tapped into a empty net after David Johnson's lob came back off the bar.
Nottm Forest: Gerrard, Louis-Jean, Hjelde, Morgan, Rogers,
Impey, Jess (Commons 68), Evans, King, Taylor, Johnson.
Subs Not Used: Roche, Westcarr, Doig, Gardner.
Booked: King, Morgan, Johnson.
Goals: Taylor 36, King 78.
Scunthorpe: Musselwhite, Stanton, Crosby, Butler, Ridley,
Beagrie, Kell, Baraclough, Taylor (Sparrow 85), Hayes,
Bailey (Parton 45).
Subs Not Used: Byrne, Williams, Evans.
Ref: K Wright (Cambridgeshire).