Nine of the party were in the squad defeated by Germany in the European Championship final this summer.
Goalkeeper Scott Loach and defenders Mancienne, Kieran Gibbs, James Tomkins, Micah Richards all return for another campaign.
The midfield quartet of Lee Cattermole, Jack Rodwell, Fabrice Muamba and Danny Rose also claimed runners-up medals.
Manager Stuart Pearce wants his side to maintain the high standards set in the tournament in Sweden.
"We've not taken an easy game and there is a reasoning behind that," he said.
"Our last few games will then have included Holland, Germany, Sweden, Spain and France, so we have played all the blue chip European countries."
England Under-21 squad to play Holland:
Frankie Fielding (Blackburn), Scott Loach (Watford); Ryan Bertrand (Reading), Kieran Gibbs (Arsenal), Michael Mancienne (Chelsea), Kyle Naughton (Tottenham), Micah Richards (Man City), James Tomkins (West Ham), Chris Smalling (Fulham); Lee Cattermole (Wigan), Fabien Delph (Aston Villa), Fabrice Muamba (Bolton), Jack Rodwell (Everton), Danny Rose (Tottenham); Andy Carroll (Newcastle), Freddie Sears (Crystal Palace), Junior Stanislas (West Ham), Daniel Sturridge (Chelsea), James Vaughan (Everton).
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