Arsenal's Emirates Stadium is to host the international friendly between Brazil and Portugal next month.
World number one side and five-times World Cup winners Brazil will face Portugal, who are seventh in the world rankings, on 6 February.
It will be a second visit to the Emirates Stadium for Brazil, who played Argentina last September.
Fulham's Craven Cottage will host a friendly between European champions Greece and South Korea on the same day.
Portugal's Brazilian coach Luiz Felipe Scolari will be making his first trip to England since rejecting the national team job last summer.
"It will be the second time I'll face Brazil since I took charge of the Portuguese team," Scolari said.
"To me it's of course a special moment and I'm really looking forward to the match."
Brazil Football Confederation (CBF) president Ricardo Teixeira added: "We are delighted to be returning to the fantastic Emirates Stadium to take on one of the best teams in the world in front of what we are sure will be another sell-out crowd."