Chelsea chief executive Peter Kenyon says Blues boss Jose Mourinho will not become the next England coach.
Mourinho has six years to run on his Chelsea contract
Sven-Goran Eriksson is leaving after this summer's World Cup, and the Football Association is keen to name his successor before the tournament.
"Mourinho has made it clear he's not interested and we'd make it quite clear we are not interested in letting him go," Kenyon told BBC Radio Five Live.
"He likes Chelsea, he and his family like London, and he is very happy."
A host of names have been linked with the post, including Sam Allardyce, Alan Curbishley, Steve McClaren, Martin O'Neill, Guus Hiddink and Luiz Felipe Scolari.
Former England boss Sir Bobby Robson, now working in the Republic of Ireland set-up, said he would prefer to see an Englishman appointed to the role.
"I would very much like to think it would go English. I'm very keen about that," he told BBC Radio Five Live.
"We've got some strong candidates in this country at this moment who are doing a great job in a very difficult league.
"The Premiership is one of the most difficult and hardest leagues there is in Europe - you could say, arguably, the best.
"And we've got some good English lads who are doing a great job with their respective clubs in that league."
Meanwhile, Middlesbrough chairman Steve Gibson has said Boro boss Steve McClaren is too inexperienced to be England manager.
"Steve has been a football manager for four years and we've had two years in the Uefa Cup. He is not a realistic candidate," he told the Independent on Sunday.
West Brom boss Bryan Robson, however, says he would be interested.
"I'd seriously consider it. I feel I have the necessary experience after nine years of management," he told the Daily Star.
Reading boss Steve Coppell is among those to rule himself out of contention, saying people who had bet on him were wasting their money.
Bobby Robson urged the FA to appoint someone with plenty of experience, pointing out his 14 years at Ipswich before becoming England boss.
"Every day I worked with the players. I found youngsters and I had time to develop the players," he said.
"That's the sort of manager we need. At the same time we need a good name, we need a strong personality and you'll find that combination if you look long enough."
Meanwhile, Eriksson has said it would be a huge handicap if his successor was not able to speak English.
Portugal boss Scolari - out of contract after the World Cup - is the only one of the main contenders who does not speak English.
Eriksson said: "When I went to Portugal in 1982 I couldn't speak any Latin languages and that was a huge handicap.
"You have to work with an interpreter and the one I had was very good in Swedish and Portuguese but he didn't know anything about football. He didn't know if the ball was square.
"I used Swedish football terms that he had never heard and I could see the players when he translated looked confused.
"It's a huge handicap if you don't speak the language in the job and in daily life. You may be out at dinner and you are sitting like a new-born child, you don't understand anything."