Cardiff City's James Collins has been dropped from the senior Wales squad to captain the Under-21 side in a Uefa Championship qualifier with Germany.
Collins will bring experience to the Wales Under-21 side
Collins won five caps under former boss Mark Hughes, but new manager John Toshack believes the 21-year-old will benefit from a step down a level.
New Under-21 boss Brian Flynn has named six uncapped players for the match in Wrexham on Tuesday, 8 February.
They include striker Joe Ledley, who has broken into Cardiff's first team.
The other are Lee Jon Beevers (Boston), Lewin Nyatanga (Derby), Tony Pulis (Portsmouth), Andy Crofts (Gillingham) and Craig Davies (Oxford).
Toshack said Collins is in the "driving seat" to partner Danny Gabbidon in Wales' next World Cup qualifier against Austria in March.
But with Wales short of experienced defenders, the new manager explained he wants to give some new players a taste of international football.
"It gives me the chance to have a look at Danny Collins and David Partridge, as well as Gabbidon," Toshack told BBC Wales Sport.
"It gives [James] Collins a bit of responsibility to go out to captain his country against a strong Germany side in a competitive match.
"Hopefully we'll be able to increase the competition for places by doing that."
Wales U-21s are fourth in qualifying Group Six, with four points from three games.
Wales Under-21 squad to play Germany in Uefa Championship Group Six qualifier at Wrexham on 8 February: Price (Ipswich), Worgan (Rushden), Beevers (Boston), Collins (capt, Cardiff), Duffy (Portsmouth), Gilbert (Plymouth), Morgan (Wrexham), Nyatanga (Derby), Fowler (Huddersfield), Ledley (Cardiff), Pipe (Notts County), Pulis (Portsmouth), Vaughan (Crewe), Jones (Wrexham), Birchall (Arsenal), Calliste (Man Utd), Crofts (Gillingham), Davies (Oxford), Tolley (Shrewsbury).