Manchester United eased to victory in their third-round replay with Burton to end the Conference side's FA Cup dream.
Giuseppe Rossi (right) scored twice for United
The result was never in doubt from the moment Louis Saha converted Kieran Richardson's cross after seven minutes.
Giuseppe Rossi rose high to head home Mikael Silvestre's cross on 22 minutes, and Richardson drove in powerfully to make it 3-0 shortly after the break.
Substitute Ryan Giggs drove in the fourth and Rossi's deflected drive in injury time completed the victory.
Backed by almost 11,000 travelling fans - the largest visiting contingent ever seen for a competitive match at Old Trafford - Burton showed no sign of nerves during the opening exchanges.
But it was United who took the lead with their first attack following a move of genuine quality.
Gerard Pique's superb pass to the left wing found Richardson in space and the midfielder picked out Saha with a low cross which the Frenchman slid home.
It was tough on the Conference side who had begun well.
But their hopes were all but ended 15 minutes later as Rossi headed United's second.
Mikael Silvestre was the provider, picking up the loose ball and sending in a perfectly-weighted cross to the Italian.
Burton remained positive and continued to play neat football, although they did not seriously threaten Tim Howard's goal.
Indeed United could have increased their lead before half time as a cross from Ole Gunnar Solskjaer eluded both Saha and Rossi by inches, then Saha dithered as he was put through by his strike partner.
However, the home team made it 3-0 soon after the break for the third, as Richardson ran clear after Rossi's astute touch and rifled a fine shot past Saul Deeney.
Saha was again guilty of taking too long as he was put through on 66 minutes, allowing Andrew Corbett to make a good tackle.
But Giggs - who came on as a 62nd-minute substitute along with England internationals Gary Neville and Rio Ferdinand, much to Burton's collective chagrin - soon grabbed the fourth as he drove in from a tight angle after the impressive Rossi put him through.
And Rossi capped a fine display as he drove in the fifth in injury time, although he was helped by a sizeable deflection.
Burton worked hard as they pressed for a consolation goal but, to the disappointment of their supporters, they found United in unforgiving mood as the home side booked their fourth-round trip to Wolves.
Man Utd: Howard, Bardsley, Pique, Brown (Neville 62), Silvestre, Solskjaer, Fletcher (Giggs 62), O'Shea (Ferdinand 62), Richardson, Rossi, Saha.
Subs Not Used: Van der Sar, van Nistelrooy.
Goals: Saha 7, Rossi 23, Richardson 52, Giggs 68, Rossi 90.
Burton Albion: Deeney, Sedgemore, Tinson, Austin, Corbett, Chris Hall (Webster 74), Stride, Ducros, Gilroy (Henshaw 86), Shaw (Anderson 26), Harrad.
Subs Not Used: Martin Taylor, Todd.
Ref: H Webb (S Yorkshire).