Tottenham kept up their 100% record in the Uefa Cup, coming from behind to beat Bruges and stay top of Group B.
Berbatov is congratulated by his team-mates after scoring for Spurs
Ibrahim Salou turned and rifled home from 20 yards to give Bruges an early lead but Dimitar Berbatov's stylish volley levelled matters minutes later.
Spurs dominated and got their reward after 63 minutes when Robbie Keane finished crisply after Berbatov flicked a volley into the Irishman's path.
The outstanding Berbatov then headed home to crown a superb Spurs display.
Spurs, who visit Bayer Leverkusen later this month, now have the knockout stages firmly in their sights - although they did have to battle back from succumbing to an early goal by Club Bruges.
The north London side had not conceded in Europe this season but the Belgian team immediately set about ruining that statistic, making a lively start.
Gaeton Englebert's snap-shot forced keeper Paul Robinson to tip the ball around the post within three minutes and the Belgian side took the lead 11 minutes later.
Ibrahim received the ball 20 yards out, with his back to goal, but turned Michael Dawson quick as a flash and fired the ball past a helpless Robinson.
The shock of going behind seemed to spur Tottenham into action and within minutes they had drawn level.
Jermaine Jenas floated in a free-kick, Pascal Chimbonda got his head to it and Berbatov back-pedalled into position on the edge of the area before volleying sweetly past Stijn Stijnen in the Bruges goal.
As the half progressed, Tottenham began to assert their authority, sweeping forward at every opportunity.
Aaron Lennon, starting on the left, caused the Belgian side problems with his pace, while Berbatov's clever distribution was also a constant threat.
A fast-flowing move involving Keane, Lennon and Berbatov should have been finished off by Hossam Ghaly but the defender blasted the ball over the bar.
Jenas should have done better from Berbatov's cute flick but the England international hit the outside of the post.
After the break it was all Tottenham but for all their possession and deft play, they could not find the finishing touch.
But Bruges were beginning to crack and when Englebert spooned a clearance from Berbatov's header back over his own crossbar, it seemed only a matter of time before Spurs went ahead.
And after 63 minutes, they were rewarded for their pressure with a superb goal.
Once again the Bulgarian Berbatov was the architect, his volleyed flick on the turn falling into the path of Keane, who - without breaking stride - found the corner of the net with a first-time strike from the edge of the area.
Tottenham showed no signs of sitting back and Berbatov soon increased their lead, getting in between two Bruges defenders to head home Ghaly's cross from the right.
Still Bruges were unable to get off the back foot as Tottenham continued to press forward and Robinson was barely troubled after the opening quarter of the game.
The England goalkeeper had a job to keep warm on a chilly night at White Hart Lane but Tottenham's performance will have warmed the heart of head coach Martin Jol as Spurs moved within touching distance of reaching the knockout stages of the Uefa Cup.
Tottenham head coach Martin Jol:
"I think the second half was our best of the season.
"We played well, we kept the ball, we had to take the initiative because they dropped off again.
"The second goal was a great goal with the combination between Dimitar Berbatov and Robbie Keane.
"I was happy for Berbatov that he played so well - it will do a lot for his confidence."
Tottenham: Robinson, Chimbonda, Dawson, King, Assou-Ekotto, Ghaly, Zokora, Jenas, Lennon (Murphy 80), Berbatov (Mido 80), Keane.
Subs Not Used: Cerny, Davids, Defoe, Huddlestone, Gardner.
Goals: Berbatov 17, Keane 63, Berbatov 73.
Club Brugge: Stijnen, Pedersen, Clement, Maertens (Vandelannoite 80), Gvozdenovic, Matondo, Vermant, Blondel, Englebert, Ibrahim, Balaban (Ishiaku 90).
Subs Not Used: Verbauwhede, Dreesen, Van Heerden, Leko, Roelandts.
Goals: Ibrahim 14.
Ref: Alberto Undiano Mallenco (Spain).