GROUP E
Frenchman Yoann Gourcuff bagged Milan's second in the San Siro
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Real Madrid's Champions League Group E campaign got off to a disastrous start as they went down 2-0 to an impressive Lyon side in the Stade Gerland.
Fred dinked the first over an advancing Iker Casillas in the Real goal, before Sidney Govou slid in Tiago to slot in.
In the group's other game Steaua Bucharest won 4-1 away at Dynamo Kiev.
Sorin Gionea gave the visitors an early lead only for Serhiy Rebrov to level. But Valentin Badea and a Nicolae Dica brace won the Romanians three points.
GROUP F
Manchester United edged out Celtic in Group F with a 3-2 victory at Old Trafford, Louis Saha scoring twice and Ole Solskjaer notching the winner.
Jan Vennegoor of Hesselink and Shunsuke Nakamura, with a brilliant 25-yard free-kick, got the Celtic goals.
In the group's other game, Portuguese side Benfica earned a valuable point away at Danish champions FC Copenhagen.
Portuguese keeper Quim was forced to make a host of fine saves as they managed to earn a 0-0 draw.
GROUP G
Last season's beaten finalists Arsenal coped well without captain Thierry Henry in Hamburg as they registered a 2-1 victory over the German side.
Gilberto Silva scored a penalty after Sascha Kirschstein was sent off and Tomas Rosicky lashed in a second before Boubacar Sanogo got a consolation.
In Group G's other game, 2004 winners FC Porto were held to a disappointing 0-0 draw at home by CSKA Moscow.
The hosts had a succession of chances but could not get past Igor Akinfeev.
GROUP H
Italian giants AC Milan made a solid if unspectacular start at home to AEK Athens in Group H with a 3-0 victory.
Filippo Inzaghi gave the Rossoneri a first-half lead with Yoann Gourcuff and a Kaka penalty wrapping things up.
Belgian side Anderlecht were denied a win 10 minutes from time by Nicolas Fauvergue's equaliser for Lille.
Nicolas Pareja put the hosts ahead just before half-time with a powerful header, only for Fauvergue to pop up with a crucial goal for the Frenchmen.