Kaiserslautern's 3-0 win over SC Freiburg last November has been named as the top-flight game under suspicion in Germany's match-fixing scandal.
German ref Robert Hoyzer admitted receiving bribes
The German Football Association (DFB) announced the findings on Thursday.
The DFB also revealed the referee at the centre of the case, Robert Hoyzer, had been involved in fixing seven cup and lower league matches.
The scandal began when in January Hoyzer admitted he had rigged games and 25 people are now under investigation.
"We are talking about organised crime here," Bundesliga chief Werner Hackmann told a news conference.
The Bundesliga first division match between Kaiserslautern and Freiburg was refereed by Juergen Jansen, who has been implicated in the case by Hoyzer but denies any involvement.
Referees Felix Zwayer and Dominik Marks are among the 25 being investigated on suspicion of manipulating 10 matches.
Of the four referees now connected with the case, only Jansen works in the top division of the Bundesliga.
"Naturally, the three referees will not be used until this is cleared up," the DFB's refereeing chief Volker Roth said in a statement.
"However, we work on the principle of presumption of innocence. If their innocence in this matter is established naturally they will return."