Toure was the creator with a cross, but Adebayor took a clever first touch before sliding a precise finish beyond Reading keeper Marcus Hahnemann.
And the advantage was deservedly doubled eight minutes later when Gilberto's long-range shot beat Hahnemann via Bikey's head.
There was still time for Hahnemann to save well from Toure and Gilberto before the half-time whistle spared Reading further punishment.
Arsenal continued to dominate after the break, but failed to make quick additions to their goals tally because of their occasionally infuriating habit of passing themselves to death rather than punishing the opposition.
Interview: Reading boss Steve Coppell
Reading captain Graeme Murty was furious just after the hour when he was felled by Alexander Hleb's flailing hand, but the incident went unnoticed by referee Peter Walton.
Van Persie was desperately unlucky after 71 minutes when he curled a stunning left-foot free-kick against the woodwork from 20 yards.
And seconds later Walcott was denied when he shot against the bar with Hahnemann beaten.
Reading almost gave Arsenal an anxious moment with 13 minutes left when Bobby Convey took advantage of slack defending, but Jens Lehmann turned his effort over the top.
But normal service was swiftly resumed and Reading substitute Duberry did well to scramble back and clear off the line from Fabregas.
• Arsenal boss Arsene Wenger: "In this match we showed what quality we do have and that the team is strong.
"We are still ambitious - we have 74 points and want to finish with 83 points which is a decent total. We want to finish off as close as we can to the winners of the league.
"We showed pride and responded after the disappointment of last week. We have to bounce back because the strong always come back stronger.
"We have a very young team with a great future."
• Reading boss Steve Coppell: "When they scored their first goal it was always going to be a mountain for us to climb.
"We shrunk back after we conceded and observed and did not play.
"After the break we put in some real effort and commitment.
"We have a three game mini-season and must aim to get enough points to stay up.
"There are nine points available to us and we have got to be genuine in our attempts to get them."
Arsenal: Lehmann, Toure (Eboue 60), Gallas, Song Billong, Clichy, Walcott, Fabregas, Silva, Hleb (Denilson 74), Van Persie, Adebayor (Bendtner 73). Subs Not Used: Mannone, Senderos.
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