Tottenham were inspired by striker Dimitar Berbatov as they came back from a goal down to beat Wigan.
Berbatov and Defoe produced unerring finishes to put Spurs ahead
Henri Camara fired in a Lee McCulloch knock-down to put Wigan ahead but Spurs hit back with two goals in 89 seconds.
Berbatov slid a pass to Jermain Defoe, who excellently turned inside Emmerson Boyce and slotted home to level, before the Bulgarian curled in Spurs' second.
Wigan tried in vain to level but Berbatov set up Lennon to add a third late on and secure a home win.
Tottenham have been criticised for their inconsistency this season and they showed the two sides to their game in the opening half as they went from lethargic to lethal.
The home side had an early chance when Lennon imaginatively flicked a high ball over three oncoming Wigan defenders to the far post.
Wigan centre-back Matt Jackson was under pressure from the influential Berbatov and his header only fell for the Spurs striker to shoot straight at keeper Chris Kirkland on the turn.
But Spurs allowed a determined Wigan to find their way into the game and paid the price by falling behind.
David Wright whipped a long diagonal ball into the Spurs box and McCulloch nodded it down for Camara to apply the finishing touch with a 15-yard strike.
Spurs re-awoke from their stupor as they pressed for an equaliser and Kirkland was forced into a double save.
The impressive Berbatov puts his side 2-1 ahead
The Wigan keeper did well to get his hand to a low, deflected Steed Malbranque effort before bravely blocking as Defoe pounced to slot in the rebound.
Lennon then left Wigan's Leighton Baines mesmerised as he beat the left-back and pulled back a pass for Malbranque from the byeline.
Malbranque was under pressure and could only shoot wide but the home fans were treated to two clinical and stylish goals in as many minutes which would have left the football purists purring.
Berbatov slid a ball to Defoe and the England striker turned on a sixpence to wrongfoot Boyce before slotting in a left-foot shot at Kirkland's near post.
Wigan barely had time to finish shaking their heads in disappointment when Berbatov touched the ball through the legs of Jackson and curled a shot into the far corner.
Wigan still seemed to be in shock after the break while Spurs had an air of authority about them as Jackson almost put a Berbatov cross past his own keeper.
The visitors regrouped and pressed for an equaliser, but Spurs held them at arm's length.
Tottenham right-back Pascal Chimbonda had been jeered by the fans of his ex-club Wigan during the game and he appeared to make a gesture to the visiting contingent late on.
And he will have come away thinking he made the right decision to move to Spurs as they wrapped up the win when Berbatov set up for Lennon to sidefoot in.
Tottenham boss Martin Jol:
"The Premiership is a tough league, at the end of the season the table does not lie and Wigan play a style which is very difficult to defend against.
"We are a footballing side, but our character came through today.
"We have the most points of the teams in the Uefa Cup, are in the Carling Cup quarter-finals and had a good win today. We can be pretty satisfied."
Wigan boss Paul Jewell
"I felt they had run out of ideas but then they got two goals in a minute or so which completely changed the complexion.
"Those minutes cost and those two goals were poor ones defensively.
"I am disappointed. We have got to try and see things out and we didn't today. Sometimes we are a bit naive."
Tottenham: Robinson, Chimbonda, Dawson, King, Assou-Ekotto, Lennon, Huddlestone, Zokora, Malbranque, Berbatov, Defoe (Keane 83).
Subs Not Used: Cerny, Lee, Davids, Murphy.
Booked: Zokora, Dawson.
Goals: Defoe 43, Berbatov 44, Lennon 90.
Wigan: Kirkland, Wright (Hall 67), Jackson, Boyce, Baines, Teale (Heskey 29), Scharner, Skoko, Kilbane (Cotterill 78), Camara, McCulloch.
Subs Not Used: Pollitt, Landzaat.
Booked: Boyce, Baines, Heskey, Skoko.
Goals: Camara 25.
Ref: M Clattenburg (Co Durham).