Results:
Aston Villa 2-1 Charlton
Fulham 2-2 Man City
Leeds 0-2 Birmingham
Liverpool 2-1 Leicester
Newcastle 0-0 Bolton
Portsmouth 1-2 Blackburn
Tottenham 1-3 Southampton
Early match: Wolves 0-5 Chelsea
Goalflashes and major incidents:
Full-time: Man City grab a point with a last-gasp equaliser at Fulham, while Southampton increase the pressure on Spurs boss Glenn Hoddle with a 3-1 win at White Hart Lane.
Elsewhere, there are away wins for Blackburn and Birmingham, and Aston Villa hold off Charlton.
But Newcastle fail again in front of goal and have to settle for a goalless draw with Bolton.
1652: GOAL Fulham 2-2 Man City
City equalise with seconds left as Paolo Wanchope heads home Sun Jihai's cross.
1650: Paul Bosvelt hits the post with an acrobatic late volley for Man City.
1647: GOAL Liverpool 2-1 Leicester
Marcus Bent sets up a nervous few final minutes for the Anfield faithful by grabbing a goal for the battling Foxes.
1645: GOAL Aston Villa 2-1 Charlton
Charlton pull one back through Kevin Lisbie - but will it be anything more than a late consolation?
1644: GOAL Leeds 0-2 Birmingham
Mikael Forsell springs the offside trap to add a second for Birmingham.
1641: GOAL Fulham 2-1 Man City
David Seaman comes out but fails to get the ball, and Louis Saha pokes home.
1637: GOAL Leeds 0-1 Birmingham
Roque Junior pulls down Mikael Forsell, and is sent off... but Paul Robinson does brilliantly to deny David Dunn from the spot. However, he is penalised for coming off his line before the kick was taken, so it is retaken by Robbie Savage, who does find the net.
1633: GOAL Liverpool 2-0 Leicester
El Hadji Diouf sets up Emile Heskey to score against his former club.
1632: GOAL Fulham 1-1 Man City
Fulham equalise through Steed Malbranque - the City defence feel he was offside but the Frenchman is allowed to convert Luis Boa Morte's cross.
1625: Villa are fortunate to escape as Charlton's Jon Fortune has a goal ruled out for a foul - replays suggest Jlloyd Samuel was felled by a team-mate rather than a Charlton player.
1621: GOAL Tottenham 1-3 Southampton
A lifeline for Spurs as Darren Anderton releases substitute Robbie Keane, who unselfishly sets up Freddie Kanoute.
1619: GOAL Tottenham 0-3 Southampton
Kevin Phillips adds a third after a fine breakaway by Saints.
1616: GOAL Portsmouth 1-2 Blackburn
Pompey pull one back as Arjan De Zeeuw heads home a Steve Stone corner.
1613: GOAL Aston Villa 2-0 Charlton
Jlloyd Samuel evades Radostin Kishishev's challenge and curls home a fine shot from the edge of the box.
1612: Kevin Phillips hit the bar as Southampton continue to dominate at White Hart Lane.
1606: GOAL Fulham 0-1 Man City
City go in front 20 seconds after the restart thanks to a Nicolas Anelka shot that takes a wicked deflection off Zat Knight.
1545: GOAL Portsmouth 0-2 Blackburn
Andy Cole turns Arjan De Zeeuw and beats Shaka Hislop to double Blackburn's lead.
1544: GOAL Tottenham 0-2 Southampton
A second for Saints, and for James Beattie - the in-form striker bends home a superb free-kick from 30 yards.
1536: GOAL Aston Villa 1-0 Charlton
Alpay volleys home a Lee Hendrie corner.
1535: GOAL Portsmouth 0-1 Blackburn
Pompey are caught napping at the back as Andy Cole's cross is allowed to reach Lucas Neill who duly finds the net.
1524: Shaun Bartlett hits the bar for Charlton.
1519: GOAL Liverpool 1-0 Leicester
Michael Owen scores from the penalty spot after Vladimir Smicer is pulled down by Gerry Taggart.
1506: Leicester are forced into an early substitution as the injured Craig Hignett is replaced by Jordan Stewart.
1504: GOAL Tottenham 0-1 Southampton
Kasey Keller concedes a needless corner, and James Beattie heads home the resulting set-piece from Matt Oakley.
1500: Saturday's seven remaining matches kick off.
1420 BST: Chelsea thrash Wolves 5-0 at Molineux to go top of the Premiership.
Team news:
Aston Villa are without the injured Olof Mellberg and Ronny Johnsen, so Alpay and Ulises De la Cruz come in, but Gareth Barry does return after suspension. Luke Young and Mark Fish are back for Charlton.
Fulham are unchanged for the visit of Man City, who bring in Danny Tiatto for Michael Tarnat, who is sidelined with a stomach bug.
Leeds make two changes, with Salomon Olembe and Ian Harte in for Seth Johnson and Didier Domi; Christophe Dugarry and Stan Laziridis start in place of Stern John and Darren Purse for Birmingham.
John Arne Riise and Emile Heskey are back in the Liverpool side following the injuries to Jamie Carragher and Milan Baros; Leicester keep the side that beat Leeds 4-0 on Monday.
Newcastle bring back Jonathan Woodgate and Nolberto Solano, while Bruno N'Gotty replaces the injured Florent Laville for Bolton.
Tim Sherwood gets a first start of the season in the Portsmouth midfield in place of the injured Patrik Berger, while Blackburn bring in Tugay for Garry Flitcroft.
Tottenham give a first start to Stehpane Dalmat in midfield, and also have Robbie Keane back on the bench after injury, while Southampton are unchanged.