Wycombe scored three times in the second half to see off 10-man Brentford and boost their play-off hopes.
Glenn Poole had put the Bees ahead with a superb 25-yard volley but the game changed when full-back Ben Starosta was sent off for lunging at Gary Holt.
Wycombe took full advantage after the break and Sergio Torres equalised when he converted John Sutton's pass.
Scott McGleish put Wanderers ahead after keeper Simon Brown dropped the ball and Sutton headed their third.
Brentford: Simon Brown, Starosta, Heywood, Osborne, Dickson, Ide, O'Connor, Smith, Poole (Sinclair 69), Thorpe, Connell (Charles 56).
Subs Not Used: Masters, Moore, Pead.
Sent Off: Starosta (45).
Goals: Poole 23.
Wycombe: Fielding, Martin, Stockley (Doherty 46), McCracken, Johnson, Bloomfield, Holt, Torres (Bullock 90), Woodman, McGleish (Daly 87), Sutton.
Subs Not Used: Christon, Oakes.
Goals: Torres 55, McGleish 61, Sutton 65.
Ref: Pat Miller (Bedfordshire).