Wycombe keeper Ricardo Batista gifted Rochdale an equaliser before redeeming himself with two fine subsequent saves.
Jermaine Easter gave Wanderers the lead from close range on 51 minutes after good work on the left from Kevin Betsy.
Easter should have doubled the lead but fired straight at Dale's Matt Gilks and he was made to pay by Kelvin Etuhu.
Etuhu broke down the right and his cross wrong-footed Batista who parried the ball into his net before later denying Gary Jones and Chris Dagnall.
Wycombe: Batista, Martin, O'Halloran, Crooks, Palmer, Betsy, Bloomfield, Doherty (Torres 70), Grant, Easter, Mooney (McParland 90).
Subs Not Used: Young, Christon, Anya.
Booked: Martin, Easter.
Goals: Easter 51.
Rochdale: Gilks, Ramsden, Goodall, Crooks (Jackson 46), McArdle, Jones, Doolan, Rundle (Thompson 76), Brown (Etuhu 56), Dagnall, Murray.
Subs Not Used: Rigby, Cooksey.
Booked: Crooks, Doolan.
Goals: Etuhu 80.
Ref: D Drysdale (Lincolnshire).