Substitute Ian Stonebridge scored just seconds after coming on to send Wycombe back to the top of League Two.
Stonebridge scored within seconds of coming on as substitute
The promotion-chasing visitors led at half-time after Tommy Mooney's cross was coolly finished by Dean Bowditch.
But County, who barely threatened in the first half, came out strongly after the break and equalised through Brian O'Callaghan's deflected shot.
But Stonebridge, on as a 75th-minute substitute, had an immediate impact as he headed in Clint Easton's free-kick.
Notts County: Pilkington, Wilson, Baudet, O'Callaghan, Pipe, Edwards (Sissoko 79), Crooks, McMahon, Needham, Dadi, Chillingworth (DeBolla 67).
Subs Not Used: Marshall, Palmer, Martin.
Booked: Pipe, McMahon.
Goals: O'Callaghan 55.
Wycombe: Talia, Senda (Collins 83), Williamson, Johnson, Easton, Betsy, Lee, Oakes (Stonebridge 75), Torres (Martin 65), Mooney, Bowditch.
Subs Not Used: Williams, Anya.
Goals: Bowditch 32, Stonebridge 76.
Ref: K Wright (Cambridgeshire).