Blackpool reaffirmed their League One promotion credentials but only after responding to a dismal first half.
Despite some excellent saves Joe Hart, the Cobblers went ahead through Simon Cox's opener in the 42nd minute.
Blackpool replacement Chris Brandon equalised four minutes into the second half before a handball by Sean Dyche saw Wes Hoolahan convert a penalty.
Brandon notched a second after 62 minutes and the luckless Dyche conceded an own goal seven minutes from time.
Blackpool: Hart, Barker, Jackson, Evatt, Williams (Coid 86), Forbes (Brandon 46), Southern, Jorgensen, Hoolahan (Gillett 85), Morrell, Parker.
Subs Not Used: Gorkss, Bean.
Goals: Brandon 49, Hoolahan 55 pen, Brandon 62, Dyche 84 og.
Northampton: Bunn, Hughes, Dyche, Pearce, Crowe, Aiston (Bojic 68), Hunt, Gilligan, Brett Johnson (Robertson 63), Cox (Kirk 76), Deuchar.
Subs Not Used: Dunn, Dolman.
Booked: Hunt, Bunn, Hughes, Aiston, Gilligan.
Goals: Cox 42.
Ref: M Russell (Hertfordshire).