Darren Anderton was sent off as Bournemouth crashed to their sixth home loss of the season.
Anderton was booked for unsporting behaviour and then dismissed following a second yellow card for dissent midway through the second half.
Keigan Parker's brace put Blackpool in command, before Simon Gillett pulled one back for Bournemouth.
But David Fox wrapped up the win for Blackpool with a fine solo effort from 20 yards in the closing stages.
Bournemouth: Moss, Hart (Pitman 59), Broadhurst, Young, Purches, Hollands (Cooper 74), Anderton, Gillett, Hayter, Fletcher, Vokes.
Subs Not Used: Stewart, Browning, Gowling.
Sent Off: Anderton (69).
Booked: Fletcher, Hayter, Anderton, Young.
Goals: Gillett 82.
Blackpool: Evans, Barker, Jackson, Evatt, Wilkinson, Forbes (Tierney 90), Bean, Jorgensen (Burgess 79), Fox, Morrell, Parker (Vernon 89).
Subs Not Used: Jones, Fernandez.
Booked: Parker, Forbes.
Goals: Parker 47, 52, Fox 88.
Ref: D Deadman (Cambridgeshire).