A late goal by Andy Robinson against his old side salvaged a point for league leaders Swansea City.
Robinson tapped in after Adebayo Akinfenwa's shot
A low, driven Simon Francis shot gave Tranmere the lead, before Owain Tudur Jones equalised with a 43rd-minute header from Kevin McLeod's cross.
Delroy Facey restored Tranmere's lead deep in first-half injury time, beating a poor offside trap for an easy strike.
But Tranmere defended too deep after the break, and Robinson tapped in when Adebayo Akinfenwa's shot was parried.
Tranmere: Achterberg, Francis, Jackson, Sharps, Goodison, Aiston (Jennings 70), Rankine, Harrison, Roberts, Greenacre (Davies 86), Facey (Zola 90).
Subs Not Used: Wilson, Dagnall.
Booked: Rankine, Goodison.
Goals: Francis 18, Facey 45.
Swansea: Gueret, Tate, Iriekpen, Monk, Ricketts, Britton (Forbes 67), Tudur-Jones, O'Leary (Martinez 45), McLeod (Robinson 45), Akinfenwa, Trundle.
Subs Not Used: Austin, Connor.
Goals: Tudur-Jones 45, Robinson 88.
Ref: M Atkinson (W Yorkshire).