Monaco's Dado Prso scored a record four goals against Deportivo
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Croatian striker Dado Prso enjoyed a birthday to remember as he helped himself to four goals in Monaco's stunning 8-3 destruction of Deportivo.
The astonishing scoreline eclipsed the records for most goals scored by one side and the highest aggregate scoreline, both achieved by Paris Saint Germain in 2000 when they beat Rosenborg 7-2.
French league leaders Monaco went in to a 4-0 lead with just half an hour gone, Jerome Rothen and Ludovic Giuly scoring before Prso bagged a quickfire double.
Diego Tristan and Lionel Scaloni gave the Spanish visitors some hope of a comeback before the break, but Prso completed his hat-trick on the stroke of half-time.
Jaroslav Plasil scored his first Champions league goal moments after the restart and Prso added his fourth soon after, before Tristan and Edouard Cisse exchanged strikes to complete the scoring.
The other game in Group C ended with Dutch side PSV Eindhoven winning 2-0 against AEK Athens, thanks to goals from Wilfred Bouma and Arjen Robben.
Group A is still wide open, with just three points separating the four teams after Wednesday's results.
Former Bayern Munich striker Giovane Elber came back to haunt his old side at the Olympic Stadium by scoring the decisive goal in Lyon's 2-1 win.
Juninho Pernambucano put the French side ahead early on with a stunning long-range free-kick past Oliver Kahn, but Dutch hitman Roy Makaay levelled just seven minutes later.
Brazilian Elber settled the tie eight minutes into the second half, slotting home from a tight angle to seal the three points for his new employers.
Celtic moved up to second in the group with an impressive display against Anderlecht at Celtic Park.
First-half strikes from Henrik Larsson, Liam Miller and Chris Sutton proved enough for Martin O'Neill's side, although Aruna Dindane did pull a goal back after the break for the Belgians.
Arsene Wenger's Arsenal kept their hopes of qualifying for the knockout stages alive with a last-gasp win over Dynamo Kiev at Highbury.
After 88 minutes of huffing and puffing the Gunners finally got their goal when England left-back Ashley Cole met Thierry Henry's header to guide the ball past the previously impregnable Olexander Shovkovskiy.
Arsenal stay bottom of Group B but they move to within a point of Russians Lokomotiv Moscow
, who held Inter Milan to a 1-1 draw in the San Siro.
Inter took an early lead through Uruguayan striker Alvaro Recoba and had a host of chances to make sure of victory.
But the Italians were punished for their profligacy in front of goal when Dmitri Loskov's shot deflected off Marco Materazzi and into the Inter net.
Sociedad's Xabi Alonso holds off Juve's Edgar Davids
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Juventus made sure of their place in the next round of the tournament with a 0-0 draw in Spain against Real Sociedad.
The Turin giants dropped their first points of the campaign but join Real Madrid in the last 16 after an uninspiring game.
Juventus were missing four key players for the tie and were indebted to goalkeeper Gianluigi Buffon for a host of fine saves which earned his side a draw.
But the Spaniards are still favourites to qualify with Juve from Group D after Olympiakos thrashed Galatasaray 3-0 to leave both sides on three points, four behind Sociedad.
Dimitris Mavrogenidis put the Greeks ahead early on and Neri Castillo doubled their advantage before half-time.
Tempers became frayed as the game wore on, with Ayhan Akman sent off for Galatasaray and Predrag Djordjevic seeing red for the hosts, before Giovanni's injury-time strike rounded off the scoring.