Page last updated at 14:49 GMT, Friday, 24 April 2009 15:49 UK
The rise and fall of the Saints - rock bottom?
With an inexperienced squad and yet another new boss in Mark Wotte, Saints have been in relegation trouble for most of the 2008-09 season.
And things have been no better off the field with the club's holding company placed in administration on 1 April 2009, one day before Lowe resigned again.
Docked 10 points, things look dire if Southampton's appeal does not succeed. From the top flight and the FA Cup final to the brink of League One in a few short years, their fall has been swift and painful.
BBC Radio Solent's Tony Husband:
"The big question now is, have we reached the bottom yet or is there worse to come?"