The Football Association will work with betting exchange Betfair to prevent match-fixing and illegal betting.
Palios aims to stamp out corruption in football
Betfair have agreed a deal which will allow the FA access to details about those suspected of corruption.
"This agreement helps us to maintain English football's well deserved reputation for integrity," said FA chief executive Mark Palios.
"The core principle of football is that players must always have winning as their sole aim within the game's laws."
Betfair is the largest online betting exchange, where individuals register with the website and can act as layers or punters on markets ranging from horse racing to cricket.
Betfair takes no bets itself, rather acts as an intermediary and claims a commission on all bets struck.
The company has also agreed similar deals with the Jockey Club, International Cricket Council and the Association of Tennis Professionals.
"This is good news for the integrity of sport," Betfair's chief executive officer Stephen Hill said.
"Working closely with sporting regulators, and allowing them access to the information we have, is the best way to ensure that sport is kept free of crime."