Sarah Taylor is set to return to the squad for the tour to India
Kent wicketkeeper Tamsin Beaumont has been included in the England women's squad to tour St Kitts later this year.
Beaumont replaces the rested Sarah Taylor in the 14-strong squad for the tour from 31 October-14 November.
Charlotte Edwards captains the side and, along with Claire Taylor, has been shortlisted for ICC Women's Cricketer of the Year to be named next month.
Taylor misses out on the West Indies tour due to her work commitments at Reading University.
England play West Indies in three ODIs and three Twenty20 matches as they prepare for the ICC World Twenty20 group stages in St Kitts next May where both Sarah Taylor and Claire Taylor will be targeting a return.
Head of England women's cricket, Clare Connor said: "As England's opening bat and wicket-keeper in all limited-overs cricket, Sarah has been through an intense period of international competition this year.
"The England management team has agreed that the next stage of her development will be best served with a focused period of physical regeneration and conditioning over the next two months."
Beaumont played an important part with the gloves and bat in the England women's academy matches against an ICC Europe XI last month.
She was also instrumental in Kent's unbeaten run in the County Championship.
Head coach, Mark Lane added, "This year has been incredible for the England women's team. After two ICC global events and the Ashes they have proved that they are unarguably the best team in the world in all formats of the game.
"My job now is to start planning for the 2013 World Cup in India and this trip to the West Indies is the first stage of that four-year process."
England: Charlotte Edwards (capt - Kent), Caroline Atkins (Sussex), Tamsin Beaumont (Kent), Katherine Brunt (Yorkshire), Holly Colvin (Sussex), Lydia Greenway (Kent), Isa Guha (Berkshire), Jenny Gunn (Notts), Danielle Hazell (Yorkshire), Laura Marsh (Sussex), Beth Morgan (Middlesex), Ebony Rainford-Brent (Surrey), Nicky Shaw (Surrey), Anya Shrubsole (Somerset)