When fielding close to the wicket you need to be on your toes to prevent quick singles being taken by the batsmen.
On occasions you'll have the opportunity to run out the batsmen.
All top fielders practise their pick up and throwing techniques as much as their batting or bowling.
So it's important to get the basics right.
Approach the ball quickly in short strides, bending the knees as you meet the ball.
Pick-up the ball with your throwing hand on the outside of the corresponding foot (ie: outside the right foot if you throw right-handed).
As you are about to take the next step the throwing hand swings back, still keeping the head down.
Release the ball early towards the target, with the palm of the hand following through on a direct path for as long as possible.