England pace bowler Simon Jones has been ruled out of the Test and one-day series against Sri Lanka after scans found a new left knee injury.
Jones had impressed on his comeback from injury
Jones has been advised to rest for another six weeks and could require more surgery if he does not recover.
"Simon had an MRI scan and his injury was reviewed by his specialist," said medical officer Dr Peter Gregory.
"His view is that Simon sustained a new injury to his knee, which has damaged the cartilage surface of the joint."
Glamorgan seamer Jones has not played for England since breaking down with an ankle injury last August.
He underwent surgery and missed the tour of Pakistan but went with the side to India, only to twist his left knee and require another operation.
He began the season well for Glamorgan but broke down again during the C&G Trophy victory over Ireland on Monday, after taking 2-23 from seven overs.
England are already without James Anderson (back) for the entire Sri Lanka series and Steve Harmison (shin) will miss the first Test at least.
Sajid Mahmood, who has played four one-day internationals, and Liam Plunkett, who played two Tests over the winter, are both expected to play at Lord's next week.
Gloucestershire's Jon Lewis is also in contention for a place in the squad, which is named on Sunday, after taking 6-49 against the tourists for England A.
If Jones' period of rest has the desired effect, his sights will be on the first Test against Pakistan, beginning at Lord's on 13 July.