Sixth one-day international, St Lucia:
West Indies 282-6 (47.1 overs) beat England 280-8 (50 overs) by four wickets
West Indies completed their second win of the weekend to take an unassailable 2-1 one-day series lead over England.
Captain Brian Lara celebrated his 35th birthday with a four-wicket win, to which he contributed a patient 57.
Shivnarine Chanderpaul got the innings started with a blistering 63 and Dwayne Bravo hit 33 not out to top England's 280-8 with 17 balls to spare.
Andrew Strauss and Michael Vaughan had both hit 67 but England's total always looked under par on a slow pitch.
England began confidently but lost momentum on a pitch slower than the one on which they had reached 281 in Saturday's five-wicket defeat.
Vaughan was the mainstay early on and he was matched by an impressive Strauss, who set a new career best.
Following the departure of Marcus Trescothick, who played on to Ravi Rampaul for 29, the duo shared a stand of 85 for the second wicket.
Vaughan's biggest chance came when a top-edged pull fell between two fielders but he survived to gain seven boundaries in all.
The stand ended only when Vaughan was run out by a spectacular throw from Ricardo Powell at square leg.
Strauss was particularly strong on the cut as he formed an effective alliance with Andrew Flintoff, worth 52.
Strauss's career-best 67 was not enough
But the increasing demands of the run rate saw Strauss the first of six wickets to fall in the last 13 overs as he was lbw attempting to sweep Chris Gayle.
Ten nagging overs from the part-time off-spinner yielded just 39 runs, with his other wicket Gareth Batty in a chaotic the final over.
Left-arm paceman Ian Bradshaw was equally miserly late in the innings.
Andrew Flintoff and Paul Collingwood should have been there to see England home but both perished to catches in the deep.
Flintoff deposited Bradshaw into the roof of the stand at midwicket but then lofted the replacement ball to mid-off for 43.
Collingwood managed a massive six off Merv Dillon on his way to 38 before an inspired bowling change saw him deposit part-time spinner Powell into the hands of Ramnaresh Sarwan at deep midwicket.
Batty followed Chris Read and Rikki Clarke back to the pavilion as England became increasingly desperate.
But just as the home side's slower bowlers had changed the course of the game, so did England's after an outstanding second wicket partnership added 97 in 13 overs.
Chanderpaul took 15 runs - 0,0,4,6,4,1 - off Darren Gough's fourth over, punishing the veteran for his lbw dismissal of Chris Gayle.
The Guyanese opener was amazed to top-edge Clarke's first ball of the weekend - a long-hop - to Batty at short midwicket.
In the previous over Batty, called in to replace Ian Blackwell in the XI, had Powell caught in the deep after an innings of 38 that included four fours and a six off Flintoff.
But the home side were unflustered as Lara and Sarwan shared a low-key partnership of 72 for the fourth wicket, of which Lara made 35.
Sarwan took 42 balls to hit a boundary and then played on to a Flintoff slower ball as he tried to repeat the shot.
Still, Lara formed partnerships with Dwayne Smith and Bravo to take the requirement to an easily-manageable 37 from 62 balls before he top-edged Harmison to fine leg.
Ridley Jacobs accompanied Bravo to the victory total with an unbeaten 19.
CH Gayle, S Chanderpaul, RL Powell, RR Sarwan, BC Lara (capt),
DR Smith, RD Jacobs, DJJ Bravo, IDR Bradshaw, R Rampaul,
England: ME Trescothick, MP Vaughan (capt), AJ Strauss, A Flintoff,
PD Collingwood, R Clarke, CMW Read, D Gough,
SJ Harmison, JM Anderson, GJ Batty.