Sussex director of cricket Peter Moores has applied to become head of the national Academy at Loughborough.
The post will become vacant in September when former Australia Test player Rod Marsh leaves in September after four years in charge.
"The appeal of the job is that you can influence positively some of the best young players in the country.
"It's one of the most important jobs in English cricket," Moores told the Brighton Argus newspaper.
He is regarded as one of the best coaches on the county circuit having taken charge at Hove seven years ago.
Moores signed a new four-year contract in 2002 after being linked with a move to Warwickshire.
Sussex promoted him to the position of director of cricket the following year and a few months later he guided the team to the first Championship title win in the club's history.
He was short-listed for the job of West Indies coach last year, only to be overlooked in favour of Australian Bennett King.
"His motivational skills are at a very high level, as are his technical skills," Sussex chief executive Hugh Griffiths told BBC Sport.
"We wouldn't want to stand in his way any more than we did when David Gilbert left us to join New South Wales."
Griffiths believes Moores may have his sights set on one day taking over as coach of the England team.
"We taken enormous pride is having produced somebody of his qualities. He is an inspiration to us all," he added.