Jimmy Anderson enjoys the adulation of his Lancashire team-mates at Hove
James Anderson's best county figures in five years helped make it a happy return to Hove for Peter Moores as Lancashire put Sussex on the back foot.
The England seamer snared three more victims to finish with 6-56 in what is likely to be his only Championship appearance of this Ashes summer.
Sussex, who had resumed day two on 247-5, were bowled out for just 289.
And although Moores' side then quickly lost two wickets, Mark Chilton (72) and Steven Croft (59) took them to 209-4.
Anderson took 3-9 in eight overs in favourable conditions during the morning session as Sussex lost their last five wickets for 42.
It was only his fourth 'six-for' for the county and was his best first-class return for Lancashire since his 6-49 against Worcestershire at Old Trafford in May 2004.
That included Ed Joyce, bowled off an inside edge by Anderson after adding just one run to his overnight 89.
Robin Martin-Jenkins (67) was floored by Anderson's yorker and Sussex's tail did not offer too much resistance, Lancashire's new skipper Glen Chapple finishing with 4-69 on a ground where he took seven wickets last season.
Lancashire's reply began disastrously when Corey Collymore claimed both openers Paul Horton and Tom Smith in nine balls either side of lunch.
It was soon 31-3 when England keeper Matt Prior took a superb diving catch to snare Francois Du Plessis cheaply.
South African Ashwell Prince then led the recovery, playing fluently for his 56 before playing on in the last over before tea.
But Chilton and Croft, expensively dropped at second slip by Luke Wright on 22, shifted the momentum firmly Lancashire's way with an unbroken stand of 107 in the evening session.
Going into day three on this slow track, they now trail by just 80 runs.
Chilton seemed to relish his move down the order to number five and will resume tomorrow having struck 11 fours, while Croft offered pugnacious support.
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