The International Cricket Council is to introduce random short-notice out-of-competition drug tests later this week.
The strengthened ICC doping code, modified to comply with the latest World Anti-Doping Agency Code, will come into force on Thursday 1 January.
"The ICC has a zero-tolerance approach to doping in cricket and this new code serves to reinforce that position," said chief executive Haroon Lorgat.
"It has just become even harder for drug cheats to get away with doping."
The code will require players to submit to testing, not only during competitions but also at any other time, with players responsible for informing the ICC of their movements.
Missed tests are the responsibility of players, who would face charges if they miss three within an 18-month time period.
In addition to subjecting players to more stringent testing conditions, the code also gives the ICC more powers to impose sanctions and penalties on players who test positive.
The ICC has signed up to the WADA code since 2006, and has been testing since 2002 but Lorgat has vowed to remain vigilant.
"We must never become complacent when it comes to protecting our sport against drug cheats," he said.
"We have recognised the threat and we have done something about it. This is a big step forward for everyone who wants to maintain clean and fair competition in cricket."