Glamorgan coach John Derrick is hopeful bowler Simon Jones will return after keyhole surgery on his left knee.
Simon Jones faces another five months on the sidelines
"It's devastating news not just for Simon but for us and England as well," Derrick told the BBC after the paceman was ruled out for five months.
"Any injury, especially to the knee with the way Simon runs into bowl, could be career-ending.
"But you just look at the way he came back much stronger, much fitter from the injury he picked up in Australia."
Jones ruptured a cruciate ligament in his right leg while fielding against Australia at Brisbane in 2002, an injury which put him out of cricket for 15 months.
There were fears then that the 27-year-old might never play again.
They've been very careful with the injury and delayed going out to America for a second opinion for a couple of weeks
But by the time of the 2005 Ashes, Jones was again a fixture in the England side and took 18 wickets at just 21.00 apiece in the first four Tests against Australia.
However an ankle injury and then continuing problems with his other knee have prevented Jones from playing for England since then.
He began the season well for Glamorgan but broke down again during the C&G Trophy victory over Ireland.
That saw him travel to the United States this week for surgery with Colorado knee specialist Richard Steadman and is now likely to miss the winter's Ashes campaign.
Steadman's previous clients have included Darren Gough and top footballers Alan Shearer, Ruud van Nistelrooy and Henrik Larsson.
"They've been very careful with the injury and delayed going out to America for a second opinion for a couple of weeks," Derrick added.
"England are dealing with the medical side but are in close contact with Chris Towers, our physio."