Australia's preparations for the forthcoming Super Series with the World XI have been hit by injuries to spinner Brad Hogg and fast bowler Shaun Tait.
Both will miss the one-day series and six-day Test, Hogg will have surgery on his knee and Tait faces three months out with an injured right shoulder.
Leg-spinner Cameron White, 22, and 30-year-old paceman Stuart Clark could both play in Wednesday's opening match.
Neither bowler has previously played at international level.
Clark, who was brought in as cover during the Ashes but was pipped for a place by Tait, has been selected for the one-day series but a decision on the Test match will be made later.
Western Australian left-arm spinner Hogg tore cartilage in training and will return home to Perth for surgery, handing a chance to Victorian spinner White.
"It's a good opportunity for an up-and-coming leg-spinner to play for Australia," said skipper Ricky Ponting.
"With a negative there always comes a positive and Cameron is a young guy who has shown his ability in domestic cricket and will be keen to show it on the international stage.
"He was identified a long time ago as an exciting young player: as well as his bowling he is excellent in the field and a good talent with the bat."
White, who has long been viewed as the successor to Shane Warne, became Victoria's youngest captain in history two years ago and claimed two wickets in his state's 12-run defeat to the world team on Sunday.
Tait is also expected to have an operation, having suffered pain whilst bowling for club South Australian club side, Sturt, on Saturday, and again while training at Telstra Dome.
Diagnostic scans revealed torn cartilage in the shoulder and Cricket Australia's medical staff said three months would be the minimum period that he would miss.