Gough recently joined Essex from Yorkshire
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Darren Gough has been invited to attend a training session with England's other specialist one-day players ahead of the series in the West Indies.
Gough, 33, was left out of the one-day squad for tours to Bangladesh and Sri Lanka late last year.
But the selectors have two pace bowling vacancies for the seven-match series in the Caribbean, beginning in April.
"Darren will bring considerable experience to the squad if selected," said chief selector David Graveney.
Gough, who recently moved counties from Yorkshire to Essex, is England's all-time leading one-day international wicket-taker, with 188 victims at an average of 24.96.
He returned from a long-term knee problem to star in England's victorious NatWest Series campaign at home last year.
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We are conscious of the fact that we may need to rest our younger bowlers
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But the demands of Test cricket subsequently proved too much and he was forced to retire from the five-day game.
Gough will undergo an initial assessment by the England medical team at the national academy at Loughborough in the next few days.
He is then scheduled to take part in a two-day training camp on 9 and 10 March.
Graveney highlighted England's heavy workload in the next six months, when the team will play at least 18 limited-overs internationals.
"We are conscious of the fact that we may need to rest our younger bowlers and rotate the seamers accordingly," he added.
"We want to assess [Gough's] form and fitness before deciding whether he should fill one of the two vacancies we currently have for seam bowlers in our one-day squad."
England's Test squad will leave for the Caribbean next Wednesday, with four Tests scheduled before the first one-day match on 18 April.