Sheffield's Kell Brook defended his British and fringe WBO intercontinental titles after a cut to Michael Jennings in the fifth round ended the bout.
The fight was an eliminator for Manny Pacquiao's WBO welterweight title.
Earlier James DeGale stopped Carl Dilks inside a round but Matthew Hall was beaten by Lukas Konecny in his European light-middleweight title challenge.
Derek Chisora also defended his British heavyweight title with victory over Commonwealth champion Sam Sexton.
Later Matthew Macklin stopped Shalva Jomardashvili in the sixth round to claim the European middleweight title.
And Frankie Gavin stopped Michael Kelly in the fifth round to claim the Irish light-welterweight crown in only his eighth pro fight.
"My heart goes out to him as everyone knows he's a nice kid," said Brook, referring to the manner of his win over Jennings.
The fight began in relatively low-key fashion with Brook making a solid start behind his jab.
We want George Groves next
Promoter Frank Warren
Brook opened up for the first time in the dying seconds of the second round with Jennings walking onto a solid right.
Jennings was proving a frustrating opponent for Brook with his movement in the fourth too sharp for the Sheffield man, but a cut above the eye to the Preston fighter in the fifth after an innocuous-looking left ended the fight.
Brook, 24, is unbeaten in 22 bouts with 15 of them ending inside the distance and is the number one contender for Philippine superstar Pacquiao's WBO belt, although that fight is unlikely to happen.
A more likely scenario is that Pacquiao, whose next fight will be at light-middleweight, will give the belt up, leaving Brook to fight for the vacant title
Earlier, DeGale looked impressive stopping Dilks for the first time in his career and secure his first professional title, the fringe WBA international super-middleweight title.
The Beijing Olympic gold medallist's movement and hand speed was too much for his opponent who was bloodied and battered by the time the fight was stopped two minutes 54 seconds into the opening round with a straight left rocking Liverpudlian Dilks.
It was unbeaten DeGale's eighth professional victory with six of those fights coming inside the scheduled distance.
"I'm very happy, obviously I didn't get out of first gear, but I'm happy," stated DeGale. "It's a stepping stone. You didn't hear him complaining about the stoppage, it was the right decision.
"Domestically I'm the best already. I'm disappointed because I trained for 10 weeks and it was over so quickly."
Afterwards DeGale's promoter Frank Warren revealed that, rather than take a fight against British super-middleweight champion Paul Smith, they want to pursue Commonwealth champion George Groves instead.
"I've offered them good money," said Warren. "They've been talking a good game. James wants the fight, I want it, so let's get it on."
Hall's fight with Konecny for the vacant European light-middleweight title was a brutal battle from the first bell.
His Czech Republic opponent shaded the first couple of close rounds, with a fierce right in the second rocking the Mancunian.
Both fighters continued to trade a barrage of clubbing punches to body and head with Konecny's shots causing Hall all sorts of trouble.
But Konecny's defence proved the tighter and he began to take full control of the fight in the fifth, hurting Hall with a fierce uppercut.
Hall was again in trouble in the sixth and was eventually floored, a combination of punches to body and face knocking the will out of the Manchester fighter.
He received a standing eight count but still managed to land a huge left on Konecny, before the Czech fighter finished the job with a two-punch combination.
After losing for the third time in his 26-fight career, Hall announced his retirement.
"He stopped me with a good shot to the body and finished it with one to the head. That's me now, I'm done," said the 26-year-old Hall.
Later, Sexton and Chisora started in lively fashion, with the latter's jab causing Sexton trouble in the second, but the Norwich fighter responded defiantly with decent combinations.
Sexton troubled Chisora with a thumping left at the start of the fourth but the Londoner responded with a looping right as the action continued at a tremendous pace.
Unbeaten Chisora, 26, started to control the fight from the fifth and the British champion rocked Sexton several times in the sixth with some slick combinations.
The pair went beyond eight rounds for the first time in their careers and the pace noticeably dropped, with Chisora still edging the fight by throwing the cleaner punches.
Chisora started the ninth in lively fashion, throwing a series of clubbing rights that rocked Sexton and, sensing victory, he finished the job with more fierce punches that gave the referee no choice but to jump in and stop the fight.
It was a tremendous performance from Chisora who took his record to 14 victories with nine knockouts.
"I knew I would outlast him and when I've got somebody on the go, I finish them. I want to go onto world level now," stated Chisora.
Macklin started at a fierce pace with his Georgian opponent feeling the full-force of the Birmingham fighter's vast array of punches.
But Jomardashvili showed he was a durable opponent and stood his ground and exchanged punches with Macklin in the third.
Slowly, Macklin started to pick apart his opponent but he himself was caught with a looping right in the fifth and that spurred the home fighter into action, hurting Jomardashvili with a barrage of body shots that left him clinging on for the bell.
It looked as if Jomardashvili had survived, but his corner decided enough was enough and they pulled their man out of the fight.
"It's nice to have the belt back and be European champion again," said Macklin.
Also on the bill, Enzo Maccarinelli lost his European cruiserweight title, knocked out in the seventh round by Alexander Frenkel, while Nathan Cleverly stopped Karo Murat in the 10th round of his WBO light-heavyweight eliminator.
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