"I'm the most devastating fighter on the planet. This is the time your career gets well and truly finished."
Haye and Harrison are former friends and training partners, but the two men traded insults at a news conference to announce the fight on Tuesday morning.
"He is a guy I groomed," added Harrison. "I have tasted his punches and power and he never hurt me in a training session.
"This is my destiny - on 13 November Audley Harrison will be champion of the world and of that there is no doubt.
"If David Haye thinks I've taken this fight strictly for a payday, he is in for a rude awakening."
Harrison is a joke - Haye
For 38-year-old Harrison, November's contest against Haye gives him the chance to fulfil his dream of winning a genuine world title.
Harrison won super heavyweight gold at the Sydney Games and was tipped to become a world champion in the professional ranks.
But his career failed to take off in any meaningful way and looked to be over when he suffered a shock points loss to Belfast taxi driver Martin Rogan in December 2008.
The 1998 Commonwealth Games champion reignited his career by winning Prizefighter last year and then scored a 12th-round knockout against Michael Sprott to win the EBU heavyweight title in April.
Listen to 5 live commentary as Haye clinches the title
Haye had hoped to meet either of the Klitschko brothers, who hold the other recognised world heavyweight titles, after beating Ruiz.
Haye's manager, Adam Booth, held talks earlier this year with Vitali (WBC) and Wladimir (WBO and IBF) about a possible unification fight but these negotiations came to nothing.
A contest between Haye and fellow Londoner Harrison, who were once close friends before a public war of words last year, will have box-office appeal in Britain, with the MEN Arena virtually guaranteed to sell out.
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