Powell takes on United States rival Tyson Gay in Gateshead at the British Grand Prix Diamond League event on Saturday.
Gay has struggled with injuries, which his doctor has put down to the strain on his body from training for the 100m discipline, but has returned to the distance to take on close friend Powell at the Diamond League events in Gateshead and Crystal Palace.
"I'm not in the shape, I believe I'm rusty. I've only done starts four times this year and had some minor setbacks, but I'm just glad to be here, healthy and out here running," Gay said.
Bolt's arrival on the scene has boosted interest in sprinting, but Gay believes the 100m was already a star-studded affair.
"Asafa made the 100m exciting, and me and him had a nice rivalry, and then Usain Bolt came along and took it to a new level," he added.
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