Fraser finished second to compatriot Veronica Campbell-Brown in the 100m in Saturday's Diamond League event
Olympic 100m champion Shelly-Ann Fraser has opted not to compete at the Commonwealth Games in Delhi in October.
The Jamaican, who took part in an IAAF Diamond League meeting on Saturday, said October was too late in the year.
The news is a blow to organisers of the Games, following men's Olympic champion Usain Bolt's decision not to compete.
Fraser said it was "too much to ask" to expect her to be in peak condition in Delhi and then come back and train for the World Championships next year.
The 23-year-old said: "It is a long season and trying to peak for the Commonwealths and then coming home in December to start training for a World Championships (next year) is too much to ask, especially for someone like me who is a also a student.
"I will be in school. I don't think I am going."
Fraser also won a gold medal as part of the Jamaican 4x100m relay squad at last year's World Championships.
She announced her decision at the Diamond League meeting in Eugene, Oregon, where she came second in the 100m behind another Jamaican, Veronica Campbell-Brown.
Double Olympic and world sprint champion Bolt announced in June he would not compete in Delhi.