Ohuruogu overturned a lifetime ban from the Olympic Games in 2007
Olympic 400m champion Christine Ohuruogu has been left out of Great Britain and Northern Ireland's team for the European Championships.
The 26-year-old has been suffering from a thigh injury and missed the recent trials in Birmingham.
Nicola Sanders has also been hampered by injuries and will only take part in the 4x400m relay in Barcelona.
Christian Malcolm has been selected for the 200m, while Dwain Chambers and James Dasaolu are in the 100m.
Mo Farah and Chris Thompson have both been selected for the 5,000 and 10,000m while Phillips Idowu will be looking to add to the World Championships triple jump gold he won last year.
Martyn Rooney will also be looking for a medal finish having twice broken 45 seconds over 400m to top the European rankings.
Double world champion Jessica Ennis, named as team captain, will be keen to win a first European title in the heptathlon with Jenny Meadows (800m) and Lisa Dobriskey (1500m) chasing podium places.
Ohuruogu missed the European Team Championships in Bergen earlier in June, after being replaced in the 400m by Sanders and pulling out of the 4x400m relay because of the quadricep muscle injury.
The London-born athlete will also miss the Super8 event in Glasgow on 7 July and the British Grand Prix in Gateshead on 10 July.
Ohuruogu won gold at the 2008 Beijing Olympics but has struggled to find her form this season, managing to finish only fourth and fifth in the opening rounds of the Diamond League.
Speaking about the injury at the trials, Ohuruogu said: "Initially we thought it was not serious but now it seems more serious and I will be out for the next few weeks.
"I'm preparing for the rest of the season as well as I can despite the setback. I am remaining positive and keeping my head focused."
UK Athletics head coach Charles van Commenee admits the absence of Ohuruogu and others could wreck his hopes of achieving a record-equalling medal haul but is confident the team will hit the target set by UK Sport.
The Dutchman said: "We have not selected the biggest possible team, but the strongest possible team. That was already clear when I decided to use the selection criteria for the World Championships.
"If we used the European standards, the team would have been much bigger. We are running a four-year programme so it doesn't make much sense to have an easy year and not be competitive at a global or Olympic level.
"That means the 2010 European Championships is all geared towards the Olympics in 2012."
He added: "Some months ago I expressed an ambition to have the best possible result of all time, which is 18 medals (in Split in 1990). That is sort of an Olympic flame - you should never give up on an ambition - but since then we've had quite a few casualties and one pregnancy so that ambition is maybe even more ambitious now.
"Nevertheless, I think we have a very good team. We have a target from UK Sport of 10-15 medals and I would be embarrassed if we would not make that target. I am confident we will do that."
The European Championships begin on 27 July.
100 metres: Dwain Chambers (Belgrave), James Dasaolu (Croydon)
200m: Christian Malcolm (Cardiff), Jeffrey Lawal Balogun (Kent)
400m: Michael Bingham (Trafford), Martyn Rooney (Croydon), Conrad Williams (Kent)
800m: Michael Rimmer (Liverpool Pembroke & Sefton)
1500m: Andy Baddeley (Harrow), Colin McCourt (Dundee Hawkhill), Tom Lancashire (Bolton)
5000m: Mo Farah (Newham & Essex Beagles), Chris Thompson (AFD)
10,000m: Mo Farah (Newham & Essex Beagles), Chris Thompson (AFD)
Marathon: Andi Jones (Salford), Lee Merrien (Newham & Essex Beagles), Ben Moreau (AFD), Dan Robinson (Stroud), Dave Webb (Leeds City), Martin Williams (Tipton)
110m hurdles: William Sharman (Belgrave), Andy Turner (Sale)
400m hurdles: David Greene (Swansea), Rhys Williams (Cardiff), Nathan Woodward (Tamworth)
4x100m relay: James Dasaolu (Croydon), Marlon Devonish (Coventry Godiva), Leon Baptiste (Enfield & Haringey), Jeffrey Lawal Balogun (Kent), Mark Lewis-Francis (Birchfield Harriers), Christian Malcolm (Cardiff), Craig Pickering (Marshall Milton Keynes)
4x400m relay: Michael Bingham (unattached), Richard Buck (City of York), Graham Hedman (Woodford Green & Essex Ladies), Martyn Rooney (Croydon), Andrew Steele (Trafford), Rob Tobin (Basingstoke & Mid Hants), Conrad Williams (Kent)
High jump: Martyn Bernard (Wakefield), Tom Parsons (Birchfield Harriers)
Long jump: Greg Rutherford (Marshall Milton Keynes), Chris Tomlinson (Newham & Essex Beagles)
Triple jump: Nathan Douglas (Oxford), Phillips Idowu (Belgrave)
Shot: Carl Myerscough (Blackpool, Wyre & Fylde)
100m: Laura Turner (Harrow)
200m: Emily Freeman (Wakefield)
400m: Lee McConnell (Shaftesbury Barnet)
800m: Jenny Meadows (Wigan), Marilyn Okoro (Shaftesbury), Jemma Simpson (Newquay & Par)
1500m: Hannah England (Bud Baldaro), Lisa Dobriskey (Ashford), Stephanie Twell (Aldershot, Farnham & District)
5000m: Jo Pavey (Exeter)
10,000m: Jo Pavey (Exeter)
3,000m steeplechase: Hatti Dean (Hallamshire), Barbara Parker (City of Norwich)
Marathon: Helen Decker (Ipswich), Susan Partridge (Leeds City), Michelle Ross-Cope (City of Stoke), Rebecca Robinson (Kendal), Holly Rush (Team Bath), Jo Wilkinson (Bedford & County)
20km walk: Joanna Jackson (Redcar)
400m hurdles: Eilidh Child (Pitreavie), Perri Shakes-Drayton (Victoria Park & Tower Hamlets)
Pole vault: Kate Dennison (Sale)
4x100m relay: Montell Douglas (Blackheath & Bromley), Katherine Endacott (City of Plymouth), Emily Freeman (Wakefield), Joice Maduaka (Woodford Green & Essex Ladies), Elaine O'Neill (Woodford Green & Essex Ladies), Laura Turner (Harrow AC)
4x400m relay: Victoria Barr (Rugby & Northampton), Lee McConnell (Shaftesbury Barnet), Marilyn Okoro (Shaftesbury Barnet), Nadine Okyere (Birchfield), Nicola Sanders (Windsor Slough Eton & Hounslow), Perri Shakes-Drayton (Victoria Park & Tower Hamlets), Kim Wall (Basildon)
Heptathlon: Jessica Ennis (City of Sheffield)