Seattle's Ichiro Suzuki broke the Major League record for hits in a season with three singles in the 8-3 victory over the Texas Rangers.
The Japanese star matched George Sisler's 84-year record of 257 with a single in the opening inning before adding another two runs to his total.
When the record fell in the third inning, the Mariners faithful gave him a standing ovation to mark the feat which has been the highlight of an otherwise disappointing season.
Elsewhere, the Minnesota Twins boosted their bid for a home start to the play-off campaign with a 4-3 victory over the Cleveland Indians.
The AL Central champions must now beat the Indians on Saturday and Sunday while hoping that Anaheim and Oakland avoid a sweep in their three-game series this weekend.
In Toronto, David Bush pitched a two-hitter for the first
complete game of his Major League career, as the Blue Jays thumped the New York Yankees 7-0.
The Yankees, who clinched their seventh straight AL East title on Thursday, only started one regular, Hideki Matsui.
Tampa Bay Devil Rays have guaranteed that they will not finish bottom of AL East for the first time in their history with a 4-1 victory over Detroit Tigers.
Tampa, who began competing in 1998, cannot be overtaken by basement side Toronto after sealing fourth place.
Chicago White Sox clinched second place in AL Central after beating Kansas City 4-2.
Jon Garland allowed two runs and five hits with three strikeouts and three walks to lead the White Sox to their eighth win in 11 games.
The San Francisco Giants kept their hopes alive of winning the NL West title with a vital 4-2 win over leaders Los Angeles Dodgers.
The victory moves the Giants to within two games of the Dodgers with two matches left in the weekend series.
Chicago Cubs are on the verge of wild-card elimination after a tense 5-4 loss to the Atlanta Braves.
The Cubs were able to score three times in the ninth inning but their comeback was not enough and now they are two games behind Houston in the wild-card standings.
Chicago must now beat the Braves on Saturday and Sunday and also hope that other results go their way.
Houston Astros bounced back from a poor start to beat the Colorado Rockies 4-2 and remain top of the NL West.
Jeff Bagwell hit a two-run homer while Mike Gallo earned the win by getting the last out of the third inning.
Philadelphia secured second place in NL East after recording a 6-2 triumph over the Florida Marlins.
Jimmy Rollins and Placido Polanco both homered while Cory Lidle pitched six solid innings.
In Cincinnati, the Reds defeated the Pittsburgh Pirates 5-1 while the New York Mets lost 4-2 at home to the Montreal Expos.