Sweden's Annika Sorenstam fired a third-round 66 to lead Korea's Gloria Park by four shots at the Samsung World Championship at Bighorn, California.
-15 A Sorenstam (Swe)
-11 Gl Park (Kor)
-10 M Wie
-9 C Matthew (Sco), C Kerr
Sixteen-year-old Michelle Wie, playing in her first professional tournament, carded a 71 and is five shots off the lead in third.
Scotland's Catriona Matthew, who also shot 71, is one shot further back.
Overnight leader Grace Park of Korea shot a 76 while American rookie Paula Creamer had a disappointing 73.
"I'm really pleased with my position," said Sorenstam.
"It was a very solid round and now I'm just looking forward to a great
"Local knowledge really helps and I've also got great memories of my win here
Wie started by three-putting the second and third in a par, bogey, double-bogey start, but salvaged her round with four birdies.
"I started off playing stupid but got smart on the back nine," she said.
"I'm pleased I managed to bring it round and that I'm still in contention. I didn't really play very well today, but hopefully tomorrow will be better."