Young Manchester United midfielder Darron Gibson has been included in the Republic of Ireland's senior panel for the first time.
Darron Gibson has been picked by Republic boss Steve Staunton
The Londonderry lad, who chose to play for the Republic rather than Northern Ireland, is in the panel for the Euro 2008 qualifier against San Marino.
Gibson, 19, is currently on loan with Belgian club Royal Antwerp.
Goalkeeper Darren Randolph of Charlton comes in as cover because number one Shay Given is out injured.
Charlton midfielder Andy Reid and Reading's Kevin Doyle are also out of the panel because of hamstring injuries.
Andy Keogh (Wolves), Stephen Hunt (Reading) and Sunderland's Anthony Stokes are all in after impressing in the recent 'B' mach with Scotland.
However, there are no places in the squad for Andy O'Brien, Clinton Morrison and Liam Miller.
The Republic, with just four points from four games, need a win before tougher games with Slovakia and Wales.
The game against San Marino takes place in the Serravalle Stadium on Wednesday, 7 February.
Republic of Ireland squad: Henderson (Brighton), Colgan (Barnsley), Randolph (Charlton), Finnan (Liverpool), Harte (Levante), McShane (West Brom), Dunne (Manchester City), Carr (Newcastle United), O'Shea, (Manchester United), Douglas (Leeds United), Carsley (Everton), McGeady (Celtic), Duff (Newcastle United), Kilbane (Wigan), Keane (Tottenham), Ireland (manchester City), Gibson (Royal Antwerp), Quinn (Sheffield United), Keogh (Wolves), Hunt (Reading), Stokes (Sunderland), Elliott (Sunderland), Quinn (Sheffield United), Long (Reading).