Five to four is one of the shortest prices in the odds-against side of evens, and is normally an indication the horse is well-fancied.
Your stake: £1 win
Horse wins: £1 profit
2/3 place: No pay-out
Your stake: £1 e/w (£2 bet)
Horse wins: £1.25 profit
2/3 place: £1.25 return (75p loss)
(Based on a handicap with more than 16 runners, such as the Grand National. The amount and number of each-way payouts varies depending on the size of field and type of race)