Kasabian release their as-yet-untitled third album in April
Kasabian will headline The Great Escape festival, which takes place in Brighton between 14 and 16 May.
The Leicester band will be joined by a host of other acts including Lightspeed Champion, Cage The Elephant, Little Boots and British Sea Power.
Metronomy and The Golden Silvers had already been announced to play at the three-day festival.
Three hundred artists will be performing across 34 venues with tickets costing from £22.50.
The new music festival is now in its fourth year and is the UK's answer to the SXSW festival in Austin, Texas.
Also joining Kasabian on the line-up will be The Black Lips, Mongrel, Chew Lips, Ipso Facto, The Pipettes, Liam Finn, Mika Miko, Ox.Eagle.Lion.Man., Beth Jeans Houghton and Hunting The Minotaur.
In previous years, The Great Escape has helped to break acts such as The Klaxons, The Kooks, Glasvegas, Gossip, Adele, Jack Penate, Gallows, Kate Nash, Sam Sparro and Crystal Castles.
Kasabian start their UK tour with Oasis on 4 June in Manchester's Heaton Park.
They also play in Sunderland, Cardiff and Edinburgh before finishing at London's Wembley Stadium on 9, 11 and 12 July.