It's two years since the old coachway was demolished in Milton Keynes.
Since that time, work has been taking place to construct a brand new Gateway to Milton Keynes.
The project has now been signed over from the council to National Express.
It will be the company's most modern facility in Britain with up to 200 coaches stopping at the coachway every day.
The official opening of the new coachway will take place in December 2010.
The full temporary closure of part of the A5130 in both directions will take place from Monday 25 October 2010 until Friday 29 April 2011.
The closure is required to enable the construction of the Milton Keynes Busway to take place. The works include the widening of the existing bridge and the dualling of the A5130 from its new junction with Fen Street
The A5130 will be closed from its junction at Northfield Roundabout to a point just before the new Coachway Road junction.
During the closure cars and buses will be able to enter the new Coachway and Park & Ride facility using the A509. Exit onto the A509 will be restricted to buses only. Cars and buses however will be able to enter and exit the Coachway Park and Ride via the A5130.
A council transport spokesman said: "During the construction period there may be some disturbance for residents and traffic in the area. We would like to apologise in advance for any inconvenience caused."