The procedure is available in about 20,000 outlets across Britain.
Teessider's are stocking up on beauty treatments despite the recession.
Botox is available in about 20,000 outlets across Britain, including many in Teesside.
And across Britain, according to The Harley Medical Group, demand for non-surgical rejuvenation procedures such as botox is up 14%.
Lynn Evans, an aesthetic practitioner in Great Ayton said clients are remaining loyal despite the economic climate.
"I found I've had a steady influx of clients coming in every month which hasn't altered during the recession." Said Lynn.
"I'll be working every day over the festive season - people like to get it to go with a new outfit - men and women alike.
"The men tend to be a bit more shy but there are a lot out there and usually prompted by their wives."
Paul Baguley is a plastic surgeon at the Cleveland Nuffield, and says there is "a huge demand" for the cosmetic treatments:
"I think this needs to be done in a controlled environment with properly qualified staff who can deal with any complications which arise.
"In the wrong place it can weaken muscles, such as a condition called 'browtosis' which leaves sufferers with the growly expression of some rugby players."
There are alternatives to injections and potions.
Light electro magnetic stimulation claims to give a non-invasive facelift, which the Broom Mill Day Spa in County Durham offers as a preventative therapy.
Therapist Gill Cheesmond thinks their popularity is down to a change in people's lifestyle :
"People don't focus on going to the pub, it's more about going to the gym and sauna then playing the computer with a glass of mineral water."
"(The treatments) are still very popular as a lot of women see they have to invest in their skin to avoid getting to the point where you need botox.
"Prevention is always better than forking out a lot of money for the cure."