Hull's Horse Guards Parade, appearing on the Sunday night
The city's Queen's Gardens and Marina plays host to a concert featuring top acts.
The free event is timed to coincide with the Clipper 09/10 Round the World Yacht Race.
The festival was launched last year to celebrate the city's links with anti-slavery champion William Wilberforce.
It features three days of live music, cabaret and street theatre.
Highlights will include Mercury Music Prize nominee Florence And The Machine, teen favourite Pixie Lott It's on the Sunday, Main Stage Queens Gardens. Midday until 5.30pm.
Raw Talent Introducing hosts some of the region's best new bands including The Gang, Silent Film Project and Mr Beasley and a host of local bands.
The festival will have live music stages in Queen's Gardens and in the Humber Street Fruit Market area near to the Marina.
The Fruit Market will be transformed with an innovative fire display over the weekend; while in Queens Gardens, Saturday's event will finish off with a spectacular firework show.
BBC Radio Humberside's Raw Talent programme will be in Queen's Gardens on Sunday, introducing bands on the stage and broadcasting performances by some of the best local acts on Sunday night.