But she was eventually captured and she died in a Nazi concentration camp.
She became famous when the diary she wrote about her experiences was published after her death.
In 2003 the awards attracted thousands of entries, and this year they're expecting even more.
Four winners will get to collect their award at the star-studded awards ceremony, plus go to Amsterdam and visit the Anne Frank Museum.
To find out more about nominations, go to the Anne Frank Trust website link on the right of this page.