Other big names at the show will be Transformers, yet another Star Wars title and the sequel to the best-selling PC game ever (and a big favourite of you lot) The Sims 2.
Fans of Digimon will also be well catered for with Digimon Racing, Digimon Rumble Arena 2 and Digimon World 4.
Nintendo is bringing a collection of games to the Game Boy Advance that first appeared on their 1980's console, the NES - including Super Mario Bros, Donkey Kong, The Legend of Zelda and Pac-Man - while their pint-sized plumber will also appear in Mario Golf and Mario Tennis.
One of the biggest games of the show is expected to be the sequel to the smash-hit adventure, Legend of Zelda: The Wind Waker.
Joystick junkies should keep their browsers hovering over Newsround's website from 12-15 May - we'll let you know what's hot and what's not, straight from Los Angeles.